CFAP70 Rekombinanter Antikörper

CFAP70 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241177C9

Kat-Nr. : 84133-5-PBS

Synonyme

241177C9, TPR repeat protein 18, TTC18

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  WB analysis using 84133-5-RR (same clone as 84133-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84133-5-RR (TTC18 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84133-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84133-5-RR

  Biolayer interferometry (BLl) kinetic assays of 84133-5-RR against Human TTC18 were performed. The affinity constant is 5.06 nM.

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Geprüfte Anwendungen

Produktinformation

84133-5-PBS bindet in WB, Indirect ELISA CFAP70 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CFAP70 fusion protein Ag35209
• Vollständiger Name: tetratricopeptide repeat domain 18
• Berechnetes Molekulargewicht: 126 kDa
• Beobachtetes Molekulargewicht: 110 kDa, 128 kDa
• GenBank-Zugangsnummer: BC032856
• Gene symbol: TTC18
• Gene ID (NCBI): 118491
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cilia- and flagella-associated protein 70 (CFAP70), also known as TTC18, harbours eight tetratricopeptide repeats (TPRs) and bound tightly to the ciliary axoneme. CFAP70 is necessary to assemble spermatid flagella and could be used as a diagnostic target for male infertility with OAT in the clinic.CFAP70 is a novel regulatory component of the ODA in motile cilia and flagella, and that the N-terminus is important for its ciliary localization (PMID: 30158508).