CFAP70 Rekombinanter Antikörper

CFAP70 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

241177C9

Kat-Nr. : 84133-5-RR

Synonyme

241177C9, TPR repeat protein 18, TTC18

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  WB analysis using 84133-5-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84133-5-RR (TTC18 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 84133-5-RR

  Biolayer interferometry (BLl) kinetic assays of 84133-5-RR against Human TTC18 were performed. The affinity constant is 5.06 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HaCaT-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

84133-5-RR bindet in WB, ELISA CFAP70 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CFAP70 fusion protein Ag35209
• Vollständiger Name: tetratricopeptide repeat domain 18
• Berechnetes Molekulargewicht: 126 kDa
• Beobachtetes Molekulargewicht: 110 kDa, 128 kDa
• GenBank-Zugangsnummer: BC032856
• Gene symbol: TTC18
• Gene ID (NCBI): 118491
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cilia- and flagella-associated protein 70 (CFAP70), also known as TTC18, harbours eight tetratricopeptide repeats (TPRs) and bound tightly to the ciliary axoneme. CFAP70 is necessary to assemble spermatid flagella and could be used as a diagnostic target for male infertility with OAT in the clinic.CFAP70 is a novel regulatory component of the ODA in motile cilia and flagella, and that the N-terminus is important for its ciliary localization (PMID: 30158508).