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TTL Rekombinanter Antikörper

TTL Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3P9

Kat-Nr. : 82763-5-PBS

Synonyme

Tubulin--tyrosine ligase, tubulin tyrosine ligase, Tubulin tyrosine ligase, EC:6.3.2.25, 3P9

Filter:
  • Western Blot (WB) analysis of various lysates using TTL Recombinant antibody (82763-5-RR)

    WB analysis using 82763-5-RR (same clone as 82763-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82763-5-RR (TTL antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82763-5-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HeLa cells using TTL Recombinant antibody (82763-5-RR)

    WB analysis of HeLa using 82763-5-RR (same clone as 82763-5-PBS)

    WB result of TTL antibody (82763-5-RR; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-TTL transfected HeLa cells. This data was developed using the same antibody clone with 82763-5-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

82763-5-PBS bindet in WB, Indirect ELISA TTL und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen TTL fusion protein Ag4526
Vollständiger Name tubulin tyrosine ligase
Berechnetes Molekulargewicht 377 aa, 43 kDa
Beobachtetes Molekulargewicht 43 kDa
GenBank-ZugangsnummerBC036819
Gene symbol TTL
Gene ID (NCBI) 150465
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tubulin-tyrosine ligase (TTL) is the enzyme responsible for the reversible addition of a tyrosine residue at the carboxyl end of alpha-tubulin. TTL forms stable complexes with tubulin and inhibit tubulin polymerization. TTL is frequently suppressed during tumor progression with resulting accumulation of detyrosinated alpha-tubulin in tumor cells. TTL suppression in human cancers is associated with increased tumor aggressiveness.