TTYH3 Polyklonaler Antikörper

TTYH3 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen(1)

Kat-Nr. : 24707-1-AP

Synonyme

hTTY3, KIAA1691, Protein tweety homolog 3, TTYH3, tweety homolog 3 (Drosophila)

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  WB analysis using 24707-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 24707-1-AP (TTYH3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HeLa-Zellen, U2OS-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below

Produktinformation

24707-1-AP bindet in WB, ELISA TTYH3 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: TTYH3 fusion protein Ag18804
• Vollständiger Name: tweety homolog 3 (Drosophila)
• Berechnetes Molekulargewicht: 523 aa, 58 kDa
• Beobachtetes Molekulargewicht: 50 kDa
• GenBank-Zugangsnummer: BC131824
• Gene symbol: TTYH3
• Gene ID (NCBI): 80727
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tweety homologs (TTYHs) are conserved transmembrane proteins present in all eukaryotes including three members (TTYH1, TTYH2, and TTYH3) in humans. They are widely expressed in mammals including at high levels in the nervous system and have been implicated in cancers and other diseases including epilepsy, chronic pain, and viral infections. Physiologically, TTYH2 and TTYH3 are broadly expressed, while expression of TTYH1 is primarily limited to the nervous system, testes, and stem cells. TTYH3 is upregulated in gastric cancer with higher expression correlated with poor clinical outcomes. (PMID: 34824283)

Publikationen

Species	Application	Title
human	WB	Cancer Biol Ther; Upregulation of TTYH3 by lncRNA LUCAT1 through interacting with ALYREF facilitates the metastasis in non-small cell lung cancer; Authors - Fang Fang