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TTYH3 Polyklonaler Antikörper

TTYH3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24707-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using TTYH3 Polyclonal antibody (24707-1-AP)

    WB analysis using 24707-1-AP (same clone as 24707-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 24707-1-AP (TTYH3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24707-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

24707-1-PBS bindet in WB, Indirect ELISA TTYH3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TTYH3 fusion protein Ag18804
Vollständiger Name tweety homolog 3 (Drosophila)
Berechnetes Molekulargewicht 523 aa, 58 kDa
Beobachtetes Molekulargewicht50 kDa
GenBank-ZugangsnummerBC131824
Gene symbol TTYH3
Gene ID (NCBI) 80727
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tweety homologs (TTYHs) are conserved transmembrane proteins present in all eukaryotes including three members (TTYH1, TTYH2, and TTYH3) in humans. They are widely expressed in mammals including at high levels in the nervous system and have been implicated in cancers and other diseases including epilepsy, chronic pain, and viral infections. Physiologically, TTYH2 and TTYH3 are broadly expressed, while expression of TTYH1 is primarily limited to the nervous system, testes, and stem cells. TTYH3 is upregulated in gastric cancer with higher expression correlated with poor clinical outcomes. (PMID: 34824283)