TWEAKR/CD266 Polyklonaler Antikörper

TWEAKR/CD266 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 19836-1-PBS

Synonyme

CD266, TNFRSF12A, TweakR, FGF-inducible 14, FGF inducible 14

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  IHC staining of mouse heart using 19836-1-AP (same clone as 19836-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 19836-1-AP (TWEAKR antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19836-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse heart using 19836-1-AP (same clone as 19836-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 19836-1-AP (TWEAKR antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19836-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

19836-1-PBS bindet in IHC, Indirect ELISA TWEAKR/CD266 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: TWEAKR/CD266 fusion protein Ag13823
• Vollständiger Name: tumor necrosis factor receptor superfamily, member 12A
• Berechnetes Molekulargewicht: 129 aa, 14 kDa
• GenBank-Zugangsnummer: BC002718
• Gene symbol: TWEAKR
• Gene ID (NCBI): 51330
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TWEAKR (also known as CD266, FN14, TNFRSF12A) is a member of the TNF receptor superfamily which is activated by its ligand, the cytokine TWEAK (TNFSF12). TWEAKR is the smallest member of the TNFR superfamily. TweakR was first described as an FGF-inducible gene that played a role in fibroblast adhesion and migration. Subsequently, the induction of TweakR expression by other growth factors and/or upon tissue injury was observed in multiple cell types, including hepatocytes, endothelial cells, adipocytes, and cardiomyocytes. (PMID: 23073510, PMID: 24409185)