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TWEAKR/CD266 Rekombinanter Antikörper

TWEAKR/CD266 Rekombinant Antikörper für Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

240991B2

Kat-Nr. : 83916-1-PBS

Synonyme

CD266, TNFRSF12A, TweakR, FGF inducible 14, DR3LG

Filter:
  • Cytometric bead array standard curve of MP00861-1

    Cytometric bead array standard curve of MP00861-1

    Cytometric bead array standard curve of MP00861-1, TWEAKR/CD266 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83916-1-PBS. Detection antibody: 83916-2-PBS. Standard: Ag13823. Range: 0.78-100 ng/mL.

  • Affinity and Kinetic Characterization of 83916-1-PBS

    Affinity and Kinetic Characterization of 83916-1-PBS

    Biolayer interferometry (BLl) kinetic assay of 83916-1-PBS against Human TWEAKR/CD266 was performed. The affinity constant is 1.04 nM.

Geprüfte Anwendungen

Produktinformation

83916-1-PBS bindet in Cytometric bead array, Indirect ELISA TWEAKR/CD266 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen TWEAKR/CD266 fusion protein Ag13823
Vollständiger Name tumor necrosis factor receptor superfamily, member 12A
Berechnetes Molekulargewicht 129 aa, 14 kDa
GenBank-ZugangsnummerBC002718
Gene symbol TWEAKR
Gene ID (NCBI) 51330
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TWEAKR (also known as CD266, FN14, TNFRSF12A) is a member of the TNF receptor superfamily which is activated by its ligand, the cytokine TWEAK (TNFSF12). TWEAKR is the smallest member of the TNFR superfamily. TweakR was first described as an FGF-inducible gene that played a role in fibroblast adhesion and migration. Subsequently, the induction of TweakR expression by other growth factors and/or upon tissue injury was observed in multiple cell types, including hepatocytes, endothelial cells, adipocytes, and cardiomyocytes. (PMID: 23073510, PMID: 24409185)