TWEAKR/CD266 Rekombinanter Antikörper

TWEAKR/CD266 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

PE Fluorescent Dye

CloneNo.

240991C5

Kat-Nr. : PE-FcA98125

Synonyme

CD266, TNFRSF12A, TweakR, 240991C5, APO3L

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  FC experiment of HT-1080 using PE-FcA98125

  1x10^6 HT-1080 cells were surface stained with 5 ul PE Anti-Human TWEAKR/CD266 Rabbit Recombinant Antibody (PE-FcA98125, Clone: 240991C5) (red), or 5 ul PE Rabbit IgG Isotype Control Recombinant Antibody (PE-FcA98136, Clone: 240953C9) (blue). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: HT-1080.Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

PE-FcA98125 bindet in FC TWEAKR/CD266 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: TWEAKR/CD266 fusion protein Ag13823
• Vollständiger Name: tumor necrosis factor receptor superfamily, member 12A
• Berechnetes Molekulargewicht: 129 aa, 14 kDa
• GenBank-Zugangsnummer: BC002718
• Gene symbol: TWEAKR
• Gene ID (NCBI): 51330
• Konjugation: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

TWEAKR (also known as CD266, FN14, TNFRSF12A) is a member of the TNF receptor superfamily which is activated by its ligand, the cytokine TWEAK (TNFSF12). TWEAKR is the smallest member of the TNFR superfamily. TWEAKR was first described as an FGF-inducible gene that played a role in fibroblast adhesion and migration. Subsequently, the induction of TWEAKR expression by other growth factors and/or upon tissue injury was observed in multiple cell types, including hepatocytes, endothelial cells, adipocytes, and cardiomyocytes. (PMID: 23073510, PMID: 24409185)