TWIST2 Monoklonaler Antikörper
TWIST2 Monoklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
Hausschwein, human, Maus, Ratte
Anwendung
WB, IHC, IF/ICC, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
1B12D11
Kat-Nr. : 66544-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66544-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA TWIST2 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten
Getestete Reaktivität | Hausschwein, human, Maus, Ratte |
Wirt / Isotyp | Maus / IgG1 |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | TWIST2 fusion protein Ag2348 |
Vollständiger Name | twist homolog 2 (Drosophila) |
Berechnetes Molekulargewicht | 160 aa, 18 kDa |
Beobachtetes Molekulargewicht | 22 kDa |
GenBank-Zugangsnummer | BC033168 |
Gene symbol | TWIST2 |
Gene ID (NCBI) | 117581 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-G-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
TWIST2, also named as BHLHA39 and DERMO1,is a basic helix-loop-helix protein which acts as a transcriptional regulator, plays a central role in differentiation of mesodermal during embryogenesis. TWIST2 inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors. It is also implicated in tumorigenesis, invasion and metastasis. TWIST2 forms both homodimers(45KD) and heterodimers with E2A E proteins, and dimer partner selection is a critical mediator of TWIST function. (PMID:14724576, 16502419).