TYRO3 Rekombinanter Antikörper

TYRO3 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250330B12

Kat-Nr. : 86404-3-PBS

Synonyme

Dtk, EC:2.7.10.1, Etk2/tyro3, Rse, Tif

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  WB analysis using 86404-3-RR (same clone as 86404-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86404-3-RR (Tyro3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86404-3-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

86404-3-PBS bindet in WB, Indirect ELISA TYRO3 und zeigt Reaktivität mit Maus, Ratten

• Getestete Reaktivität: Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: TYRO3 fusion protein Eg2918
• Vollständiger Name: TYRO3 protein tyrosine kinase 3
• Berechnetes Molekulargewicht: 96 kDa
• Beobachtetes Molekulargewicht: 130 kDa
• GenBank-Zugangsnummer: NM_019392.2
• Gene symbol: Tyro3
• Gene ID (NCBI): 22174
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

YRO3 has a structure includes a cytoplasmic domain and an extracellular ligand binding region. And ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. TYRO3 is associated with many physiological processes including cell survival, migration and differentiation. It has been reported that TYRO3 can be expressed in various regions of the mammalian central nervous system. The molecular mass of TYRO3 is 130 kDa, the apparent molecular mass is higher due to glycosylation.((PMID: 8873131, 23354874, 21539887)