Telethonin Polyklonaler Antikörper

Telethonin Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 16104-1-PBS

Synonyme

TCAP, CMD1N

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  WB analysis using 16104-1-AP (same clone as 16104-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16104-1-AP (Telethonin antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16104-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse heart using 16104-1-AP (same clone as 16104-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 16104-1-AP (Telethonin antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16104-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse skeletal muscle using 16104-1-AP (same clone as 16104-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 16104-1-AP (Telethonin antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16104-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

16104-1-PBS bindet in WB, IHC, Indirect ELISA Telethonin und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Telethonin fusion protein Ag9014
• Vollständiger Name: titin-cap (telethonin)
• Berechnetes Molekulargewicht: 167 aa, 19 kDa
• Beobachtetes Molekulargewicht: 19 kDa
• GenBank-Zugangsnummer: BC012628
• Gene symbol: TCAP
• Gene ID (NCBI): 8557
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Telethonin, also known as TCAP, is a sarcomeric protein found exclusively in striated and cardiac muscle, where it localizes to the periphery of Z discs that define the border of the sarcomere. It binds to the N-terminus of myoglobin, effectively increasing its mechanical resistance. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G(PMID: 19679566).