Teneurin 1 Polyklonaler Antikörper

Teneurin 1 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21696-1-PBS

Synonyme

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  WB analysis of H69/H146 cells using 21696-1-AP (same clone as 21696-1-PBS)

  WB result of anti-ODZ1 (21696-1-AP) with two cell lines by Dr. Petrini, Iacopo. This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

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  WB analysis using 21696-1-AP (same clone as 21696-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21696-1-AP (ODZ1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

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  WB analysis of human brain using 21696-1-AP (same clone as 21696-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 21696-1-AP (ODZ1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse brain using 21696-1-AP (same clone as 21696-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 21696-1-AP (ODZ1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human brain using 21696-1-AP (same clone as 21696-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 21696-1-AP (ODZ1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human brain using 21696-1-AP (same clone as 21696-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 21696-1-AP (ODZ1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 21696-1-AP (same clone as 21696-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21696-1-AP (Teneurin 1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 21696-1-AP (same clone as 21696-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21696-1-AP (Teneurin 1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

21696-1-PBS bindet in WB, IHC, Indirect ELISA Teneurin 1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Teneurin 1 fusion protein Ag16289
• Vollständiger Name: odz, odd Oz/ten-m homolog 1(Drosophila)
• Berechnetes Molekulargewicht: 2732 aa, 306 kDa
• Beobachtetes Molekulargewicht: 305 kDa
• GenBank-Zugangsnummer: BC140783
• Gene symbol: Teneurin 1
• Gene ID (NCBI): 10178
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ODZ1 (also known as teneurin-1, TENM1), which plays a key role in central nervous system ontogenesis. ODZ1 is upregulated in Glioblastoma cells through a Stat3-mediated pathway activated by IL-6, which is released by tumor-associated monocytes. In addition, a hypoxic microenvironment regulates GBM tumor cell migration in part by inducing ODZ1 through hypomethylation of a CpG island in the ODZ1 promoter.