NeutraKine® Thrombin-Coagulation FactorII Monoklonaler Antikörper

NeutraKine® Thrombin-Coagulation FactorII Monoklonal Antikörper für Neutralization, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

Neutralization, ELISA

Konjugation

Unkonjugiert

CloneNo.

2G3G10

Kat-Nr. : 69014-1-Ig

Synonyme

Coagulation factor II, F2, NeutraKine® Thrombin-Coagulation FactorII, Prothrombin, PT

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Galerie der Validierungsdaten

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  Neutralization experiment of NeutraKine® Thrombin-Coagulation FactorII using 69014-1-Ig

  Recombinant human Thrombin (Cat.NO. HZ-3010) catalyzes Spectrozyme PL to form chromophore (monitored absorbance at 405 nm) in a dose dependent manner (left pannel). The activity of Thrombin (400ng/mL HZ-3010) was inihibited by serial dose of anti-Thrombin monoclonal antibody 69014-1-Ig (right pannel). The typically ND50 is 5-20 μg/mL.

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Neutralization

Produktinformation

69014-1-Ig bindet in Neutralization, ELISA NeutraKine® Thrombin-Coagulation FactorII und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: human Humankine Thrombin-Coagulation FactorII protein HZ-3010
• Vollständiger Name: coagulation factor II (prothrombin)
• Gene symbol: F2
• Gene ID (NCBI): 2147
• Konjugation: Unkonjugiert
• Form: Lyophilized Powder
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: Sterile PBS.
• Endotoxin: <0.1 EU/μg
• Wiederherstellung: This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
• Stability and Storage: Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

Hintergrundinformationen

Normal blood coagulation is a complex process, involving a cascade of activation of different plasma proteins, ultimately resulting in the formation of a clot, called fibrin. Factor II, or prothrombin, is one of the components of this chain of plasma proteins involved in blood coagulation. Thrombin is essential in the processes of hemostasis and thrombosis.

This antibody can be used to neutralize the bioactivity of Thrombin-Coagulation FactorII.