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Thrombospondin 1 Monoklonaler Antikörper

Thrombospondin 1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2A3E1

Kat-Nr. : 67241-1-PBS

Synonyme

THBS, THBS 1, THBS1, thrombospondin 1, Thrombospondin-1, TSP, TSP 1, TSP1, TSP-1

Filter:
  • Western Blot (WB) analysis of various lysates using Thrombospondin 1 Monoclonal antibody (67241-1-Ig)

    WB analysis using 67241-1-Ig (same clone as 67241-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67241-1-Ig (THBS1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67241-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of NIH/3T3 cells using Thrombospondin 1 Monoclonal antibody (67241-1-Ig)

    WB analysis of NIH/3T3 using 67241-1-Ig (same clone as 67241-1-PBS)

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 67241-1-Ig (Thrombospondin 1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67241-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of rat spleen tissue using Thrombospondin 1 Monoclonal antibody (67241-1-Ig)

    WB analysis of rat spleen using 67241-1-Ig (same clone as 67241-1-PBS)

    rat spleen tissue were subjected to SDS PAGE followed by western blot with 67241-1-Ig (THBS1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67241-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67241-1-PBS bindet in WB, Indirect ELISA Thrombospondin 1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen Thrombospondin 1 fusion protein Ag29129
Vollständiger Name thrombospondin 1
Berechnetes Molekulargewicht 129 kDa
Beobachtetes Molekulargewicht 160 kDa
GenBank-ZugangsnummerNM_003246
Gene symbol Thrombospondin 1
Gene ID (NCBI) 7057
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Thrombospondin 1(TSP-1), an extracellular matrix protein, is the first identified natural angiogenesis inhibitor. A variety of normal cells, including endothelial cells, fibroblasts, adipocytes, smooth muscle cells, monocytes, macrophages, and transformed cells such as malignant glioma cells, secrete Thrombospondin 1. It regulates cellular phenotype during tissue genesis and repair. It acts as a molecular facilitator by bringing together cytokines, growth factors, matrix components, membrane receptors and extracellular proteases. Thrombospondin 1 binds to a wide variety of integrin and non-integrin cell surface receptors. It is also a major activator of transforming growth factor (TGFβ1). Secreted TSP1 is a glycoprotein with a molecular mass of 150-180 kDa.