Thyroglobulin Monoklonaler Antikörper

Thyroglobulin Monoklonal Antikörper für IHC, IF-P, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

IHC, IF-P, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

4D3C5

Kat-Nr. : 60272-1-PBS

Synonyme

TG, 4D3C5

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  IHC staining of human thyroid using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human thyroid using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IF Staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human thyroid cancer tissue using Thyroglobulin antibody (60272-1-Ig, Clone: 4D3C5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IF Staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human thyroid cancer tissue using Thyroglobulin antibody (60272-1-Ig, Clone: 4D3C5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IF Staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human thyroid cancer tissue using Thyroglobulin antibody (60272-1-Ig, Clone: 4D3C5 ) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

60272-1-PBS bindet in IHC, IF-P, Indirect ELISA Thyroglobulin und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Thyroglobulin fusion protein Ag18070
• Vollständiger Name: thyroglobulin
• Berechnetes Molekulargewicht: 2768 aa, 305 kDa
• GenBank-Zugangsnummer: BC140933
• Gene symbol: Thyroglobulin
• Gene ID (NCBI): 7038
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.