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Tie-2/CD202b Rekombinanter Antikörper

Tie-2/CD202b Rekombinant Antikörper für IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241753F12

Kat-Nr. : 84469-5-PBS

Synonyme

241753F12, Angiopoietin-1 receptor, CD202b, EC:2.7.10.1, Endothelial tyrosine kinase

Filter:
  • Immunofluorescence (IF) / fluorescent staining of bEnd.3 cells using Tie-2/CD202b Recombinant antibody (84469-5-RR)

    IF Staining of bEnd.3 using 84469-5-RR (same clone as 84469-5-PBS)

    Immunofluorescent analysis of (4% PFA) fixed bEnd.3 cells using Tie-2 antibody (84469-5-RR, Clone: 241753F12 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84469-5-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84469-5-PBS bindet in IF/ICC, Indirect ELISA Tie-2/CD202b und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Tie-2/CD202b fusion protein Eg1514
Vollständiger Name endothelial-specific receptor tyrosine kinase
Berechnetes Molekulargewicht126kDa
GenBank-ZugangsnummerNM_001290549.1
Gene symbol Tek
Gene ID (NCBI) 21687
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tie-2, or TEK, is a receptor tyrosine kinase (RTK) specifically expressed in endothelial cells. It plays a crucial role in angiogenesis, forming new blood vessels, and maintaining vascular stability. Tie-2 is a member of the Tie receptor family, characterized by the presence of immunoglobulin and epidermal growth factor (EGF) homology domains. Tie-2 plays a significant role in several vascular diseases, including vascular malformations like venous malformations. It is also implicated in pathological vascular remodeling associated with tumor growth, where it is often overexpressed in tumor vessels.