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Tie-2/CD202b Rekombinanter Antikörper

Tie-2/CD202b Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250234F8

Kat-Nr. : 86010-2-PBS

Synonyme

TEK, Angiopoietin 1 receptor, Angiopoietin-1 receptor, CD202B, EC:2.7.10.1

Filter:
  • Western Blot (WB) analysis of human placenta tissue using Tie-2/CD202b Recombinant antibody (86010-2-RR)

    WB analysis of human placenta using 86010-2-RR (same clone as 86010-2-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 86010-2-RR (TEK antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86010-2-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HUVEC cells using Tie-2/CD202b Recombinant antibody (86010-2-RR)

    WB analysis of HUVEC using 86010-2-RR (same clone as 86010-2-PBS)

    HUVEC cells were subjected to SDS PAGE followed by western blot with 86010-2-RR (TEK antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86010-2-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86010-2-PBS bindet in WB, Indirect ELISA Tie-2/CD202b und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Tie-2/CD202b fusion protein Eg3367
Vollständiger Name TEK tyrosine kinase, endothelial
Berechnetes Molekulargewicht 1124 aa, 126 kDa
Beobachtetes Molekulargewicht120 kDa, 160 kDa
GenBank-ZugangsnummerBC035514
Gene symbol Tie2
Gene ID (NCBI) 7010
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tie2 (also known as TEK) is a tyrosine-protein kinase expressed almost exclusively on endothelial cells. It contains two immunoglobulin-like domains, three epidermal growth factor (EGF)--like domains and three fibronectin type III repeats. Tie2 acts as a cell-surface receptor for ANGPT1, ANGPT2, and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Mutations in the gene Tie2 are associated with inherited venous malformations of the skin and mucous membranes. Human Tie2 has a calculated molecular weight of 126 kDa. As a result of glycosylation, the apparent molecular mass of Tie2 is approximately 140-160 kDa.