• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Tie-2/CD202b Rekombinanter Antikörper

Tie-2/CD202b Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250234B4

Kat-Nr. : 98462-3-PBS

Synonyme

TEK, Angiopoietin 1 receptor, Angiopoietin-1 receptor, CD202B, EC:2.7.10.1

Filter:
  • Flow cytometry (FC) experiment of HUVEC cells using Anti-Human Tie-2/CD202b Rabbit Recombinant Antibod (98462-3-RR)

    FC experiment of HUVEC using 98462-3-RR (same clone as 98462-3-PBS)

    1x10^6 HUVEC cells (left) or 293T cells (right) were surface stained with 0.15 ug Anti-Human Tie-2/CD202b Rabbit RecAb (98462-3-RR, Clone: 250234B4) or 0.15 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L)(red). Cells were not fixed. This data was developed using the same antibody clone with 98462-3-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

98462-3-PBS bindet in FC Tie-2/CD202b und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Tie-2/CD202b fusion protein Eg3367
Vollständiger Name TEK tyrosine kinase, endothelial
Berechnetes Molekulargewicht 1124 aa, 126 kDa
GenBank-ZugangsnummerBC035514
Gene symbol Tie2
Gene ID (NCBI) 7010
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C.

Hintergrundinformationen

Tie-2, also known as CD202b or TEK, is a receptor tyrosine kinase (RTK) specifically expressed in endothelial cells. It plays a crucial role in angiogenesis, forming new blood vessels, and maintaining vascular stability. Tie-2 is a member of the Tie receptor family, characterized by the presence of immunoglobulin and epidermal growth factor (EGF) homology domains. Tie-2 plays a significant role in several vascular diseases, including vascular malformations like venous malformations. It is also implicated in pathological vascular remodeling associated with tumor growth, where it is often overexpressed in tumor vessels.