Tissue Factor/CD142 Rekombinanter Antikörper

Tissue Factor/CD142 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

240784E2

Kat-Nr. : 98104-1-RR

Synonyme

CD142, Coagulation factor III, F3, Tissue factor, 240784E2

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  FC experiment of human PBMCs using 98104-1-RR

  1x10^6 untreated or LPS-treated human PBMCs were surface stained with 0.25 ug Anti-Human Tissue Factor/CD142 Rabbit RecAb (98104-1-RR, Clone: 240784E2) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

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  Affinity and Kinetic Characterization of 98104-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98104-1-RR against Human Tissue Factor/CD142 were performed. The affinity constant is 0.834 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: LPS treated human PBMCs

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98104-1-RR bindet in FC Tissue Factor/CD142 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Tissue Factor/CD142 fusion protein Eg1052
• Vollständiger Name: coagulation factor III (thromboplastin, tissue factor)
• Berechnetes Molekulargewicht: 33 kDa
• GenBank-Zugangsnummer: NM_001993.5
• Gene symbol: F3
• Gene ID (NCBI): 2152
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

Normal blood coagulation is a complex process, involving a cascade of activation of different plasma proteins, ultimately resulting in the formation of a clot, called fibrin. Tissue Factor (TF), also named CD142, coagulation factor III or F3, is the primary initiator of the blood coagulation cascade and plays an essential role in hemostasis (PMID: 26877187; PMID: 33796108).