Toca 1 Polyklonaler Antikörper

Toca 1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55055-1-PBS

Synonyme

---

• 

  WB analysis of mouse brain using 55055-1-AP (same clone as 55055-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 55055-1-AP (Toca 1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55055-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

55055-1-PBS bindet in WB, Indirect ELISA Toca 1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: formin binding protein 1-like
• Berechnetes Molekulargewicht: 70 kDa
• Beobachtetes Molekulargewicht: 63-75 kDa
• GenBank-Zugangsnummer: NM_017737
• Gene symbol: Toca 1
• Gene ID (NCBI): 54874
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Toca-1, also named as FNBP1L or C1orf39, belongs to the FNBP1 family. It is required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Toca-1 may bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. The antibody is specific to Toca-1.