Transferrin/TF Rekombinanter Antikörper

Transferrin/TF Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

5O7

Kat-Nr. : 81676-1-PBS

Synonyme

TF, transferrin, Serotransferrin, PRO2086, PRO1557

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  WB analysis using 81676-1-RR (same clone as 81676-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 81676-1-RR (Transferrin antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 81676-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 81676-1-RR (same clone as 81676-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 81676-1-RR (Transferrin antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 81676-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human hepatocirrhosis using 81676-1-RR (same clone as 81676-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis tissue slide using 81676-1-RR (Transferrin antibody) at dilution of 1:950 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81676-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human hepatocirrhosis using 81676-1-RR (same clone as 81676-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis tissue slide using 81676-1-RR (Transferrin antibody) at dilution of 1:950 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81676-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

81676-1-PBS bindet in WB, IHC, Indirect ELISA Transferrin/TF und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Transferrin/TF fusion protein Ag11504
• Vollständiger Name: transferrin
• Berechnetes Molekulargewicht: 698 aa, 77 kDa
• Beobachtetes Molekulargewicht: 77 kDa
• GenBank-Zugangsnummer: BC059367
• Gene symbol: TF
• Gene ID (NCBI): 7018
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Serotransferrin(TF) is a 77 kDa secreted protein which is also named as transferrin, siderophilin, beta-1 metal-binding globulin and belongs to a family of homologous iron-binding glycoproteins that encompasses lactoferrin (found both intracellular and in secretions, including milk), melanotrasferrin (present on melanoma cells) and ovotransferrin (present in egg white). TF is a multi-function protein with a primary role in transporting iron in a safe, redox-inactive state from absorption to utilization or storage sites around the body. The association of Tf with the immune system derives from its ability to restrict serum free-iron levels, creating low-iron environments where the infection capacity of pathogenic microorganisms is limited. TF is expressed predominantly in the liver and secreted in plasma, but lower amounts can be synthesized in other tissues such as the brain and the testis.