TrkB Rekombinanter Antikörper

TrkB Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250617A8

Kat-Nr. : 85971-3-PBS

Synonyme

BDNF/NT-3 growth factors receptor, EC:2.7.10.1, GP145-TrkB/GP95-TrkB, Neurotrophic tyrosine kinase receptor type 2, Ntrk2

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  WB analysis of mouse brain using 85971-3-RR (same clone as 85971-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85971-3-RR (TrkB antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85971-3-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

85971-3-PBS bindet in WB, Indirect ELISA TrkB und zeigt Reaktivität mit Maus, Ratten

• Getestete Reaktivität: Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: TrkB fusion protein Eg3000
• Vollständiger Name: neurotrophic tyrosine kinase, receptor, type 2
• Berechnetes Molekulargewicht: 92 kDa
• Beobachtetes Molekulargewicht: 90-95 kDa, 140-145 kDa
• GenBank-Zugangsnummer: NM_001025074.3
• Gene symbol: Ntrk2
• Gene ID (NCBI): 18212
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tropomyosin-related kinase B (TrkB) is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. It is a single-pass type 1 membrane protein consisting of three domains: an extracellular ligand binding domain, a transmembrane domain and an intracellular tyrosine kinase domain. TrkB is primarily expressed in the central and peripheral nervous systems. TrkB plays an important role in neural development and maintenance through regulating neuronal differentiation, proliferation, survival, migration, neurogenesis, and plasticity.