UBAP2L Monoklonaler Antikörper

UBAP2L Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

1E3D1

Kat-Nr. : 67588-1-Ig

Synonyme

1E3D1, KIAA0144, NICE 4, NICE4, Protein NICE 4

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  WB analysis of K-562 using 67588-1-Ig

  K-562 cells were subjected to SDS PAGE followed by western blot with 67588-1-Ig (UBAP2L antibody) at dilution of 1:1700 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HEK-293 using 67588-1-Ig

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 67588-1-Ig (UBAP2L antibody) at dilution of 1:1700 incubated at room temperature for 1.5 hours.

• 

  WB analysis of LNCaP using 67588-1-Ig

  LNCaP cells were subjected to SDS PAGE followed by western blot with 67588-1-Ig (UBAP2L antibody) at dilution of 1:1700 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HEK-293-Zellen, K-562-Zellen, LNCaP-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

67588-1-Ig bindet in WB, ELISA UBAP2L und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: UBAP2L fusion protein Ag30125
• Vollständiger Name: ubiquitin associated protein 2-like
• Berechnetes Molekulargewicht: 115 kDa
• Beobachtetes Molekulargewicht: 140-160 kDa
• GenBank-Zugangsnummer: BC003170
• Gene symbol: UBAP2L
• Gene ID (NCBI): 9898
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Ubiquitin-associated protein 2-like (UBAP2L) is a highly conserved protein with an N-terminal ubiquitin-associated (UBA) domain involved in the ubiquitin-proteasome system and aggregate formation induced by proteasome inhibitors. It was originally identified as a human sperm protein that interacts with zona pellucida 3 in human eggs. It can interact with BIM1 to form a complex that modulates hematopoietic stem cell activity. Recent studies have confirmed that UBAP2L function as an oncogene and is associated with various types of cancer, including prostate cancer, glioma, hepatocellular carcinoma (HCC), and colorectal carcinoma. (PMID: 31114027, PMID: 29196913)