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UGT1A6 Polyklonaler Antikörper

UGT1A6 Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13127-2-AP

Synonyme

GNT1, HLUGP, HLUGP1, UDPGT, UDPGT 1 6, UGT 1F, UGT1, UGT1 06, UGT1*6, UGT1.6, UGT1A6, UGT1A6S, UGT1F

Galerie der Validierungsdaten

Geprüfte Anwendungen

Veröffentlichte Anwendungen

WBSee 2 publications below
IHCSee 2 publications below

Produktinformation

13127-2-AP bindet in WB, IHC, ELISA UGT1A6 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
In Publikationen genannte Reaktivitäthuman, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen UGT1A6 fusion protein Ag3792
Vollständiger Name UDP glucuronosyltransferase 1 family, polypeptide A6
Berechnetes Molekulargewicht 532 aa, 61 kDa
GenBank-ZugangsnummerBC019861
Gene symbol UGT1A6
Gene ID (NCBI) 54578
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

UGT1A6 belongs to the UDP-glycosyltransferase family functioning to catalyze the transfer of glycosyl groups to lipophilic substrates, which play a key role in the inactivation and elimination of many endogenous and exogenous compounds. UGT1A6 is responsible for the glucuronida-tion of many xenobiotics and several drugs, like paracetamol, valproate,and deferiprone. It also metabolizes several important endogenous substrates such as serotonin. Polymorphisms exists in UGT1A6 gene. Studies have demonstrated very widespread variability in the expression of UGT1A6 in liver.

Publikationen

SpeciesApplicationTitle
rat, humanWB,IHC

Cancer Chemother Pharmacol

Evaluation of resveratrol sensitivities and metabolic patterns in human and rat glioblastoma cells.

Authors - Sun Zheng Z
View Article
ratWB, IHC

Neurotherapeutics

Diffusion Efficiency and Bioavailability of Resveratrol Administered to Rat Brain by Different Routes: Therapeutic Implications.

Authors - Xiao-Hong Shu
View Article