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UNC13A Rekombinanter Antikörper

UNC13A Rekombinant Antikörper für IF/ICC, IF-P, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

IF/ICC, IF-P, ELISA

Konjugation

Unkonjugiert

CloneNo.

230469G2

Kat-Nr. : 83000-6-PBS

Synonyme

Munc13-1, Protein unc-13 homolog A, Protein unc 13 homolog A, Munc13 1, KIAA1032

Filter:
  • Immunofluorescence (IF) / fluorescent staining of rat brain tissue using UNC13A Recombinant antibody (83000-6-RR)

    IF Staining of rat brain using 83000-6-RR (same clone as 83000-6-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded rat brain tissue using UNC13A antibody (83000-6-RR, Clone: 230469G2 ) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83000-6-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of rat brain tissue using UNC13A Recombinant antibody (83000-6-RR)

    IF Staining of rat brain using 83000-6-RR (same clone as 83000-6-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded rat brain tissue using UNC13A antibody (83000-6-RR, Clone: 230469G2 ) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83000-6-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of SH-SY5Y cells using UNC13A Recombinant antibody (83000-6-RR)

    IF Staining of SH-SY5Y using 83000-6-RR (same clone as 83000-6-PBS)

    Immunofluorescent analysis of (4% PFA) fixed SH-SY5Y cells using UNC13A antibody (83000-6-RR, Clone: 230469G2 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83000-6-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

83000-6-PBS bindet in IF/ICC, IF-P, ELISA UNC13A und zeigt Reaktivität mit human, Ratten

Getestete Reaktivität human, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name unc-13 homolog A (C. elegans)
Berechnetes Molekulargewicht 193 kDa
GenBank-ZugangsnummerNM_001080421
Gene symbol UNC13A
Gene ID (NCBI) 23025
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

UNC13A, also named KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in INS secretion. The antibody is specific to UNC13A.