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UNC5A-Specific Polyklonaler Antikörper

UNC5A-Specific Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20239-1-PBS

Synonyme

KIAA1976, Netrin receptor UNC5A, Protein unc-5 homolog 1, Protein unc-5 homolog A, UNC5A

Filter:
  • Western Blot (WB) analysis of various lysates using UNC5A-Specific Polyclonal antibody (20239-1-AP)

    WB analysis using 20239-1-AP (same clone as 20239-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20239-1-AP (UNC5A-Specific antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20239-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse brain tissue using UNC5A-Specific Polyclonal antibody (20239-1-AP)

    WB analysis of mouse brain using 20239-1-AP (same clone as 20239-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 20239-1-AP (UNC5A-Specific antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20239-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

20239-1-PBS bindet in WB, Indirect ELISA UNC5A-Specific und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name unc-5 homolog A (C. elegans)
Berechnetes Molekulargewicht 93 kDa
Beobachtetes Molekulargewicht 103 kDa
GenBank-ZugangsnummerNM_133369
Gene symbol UNC5A
Gene ID (NCBI) 90249
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

UNC5A, also named as KIAA1976 and UNC5H1, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5A. It has no cross reaction to UNC5B, UNC5C and UNC5D.