UNC5A-Specific Rekombinanter Antikörper

UNC5A-Specific Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251526D11

Kat-Nr. : 86582-1-PBS

Synonyme

KIAA1976, Netrin receptor UNC5A, Protein unc-5 homolog 1, Protein unc-5 homolog A, UNC5A

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  WB analysis using 86582-1-RR (same clone as 86582-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86582-1-RR (UNC5A-Specific antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86582-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

86582-1-PBS bindet in WB, Indirect ELISA UNC5A-Specific und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: unc-5 homolog A (C. elegans)
• Berechnetes Molekulargewicht: 93 kDa
• Beobachtetes Molekulargewicht: 103 kDa
• GenBank-Zugangsnummer: NM_133369
• Gene symbol: UNC5A
• Gene ID (NCBI): 90249
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

UNC5A, also named as KIAA1976 and UNC5H1, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.