UNC5D-Specific Polyklonaler Antikörper

UNC5D-Specific Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen(1)

Kat-Nr. : 20241-1-AP

Synonyme

KIAA1777, Netrin receptor UNC5D, PRO34692, Protein unc 5 homolog 4, Protein unc 5 homolog D, unc 5 homolog D (C. elegans), UNC5D, Unc5h4

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  WB analysis of mouse kidney using 20241-1-AP

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 20241-1-AP (UNC5D-Specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse kidney using 20241-1-AP

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 20241-1-AP (UNC5D-Specific antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Mausnierengewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

20241-1-AP bindet in WB, ELISA UNC5D-Specific und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: unc-5 homolog D (C. elegans)
• Berechnetes Molekulargewicht: 106 kDa
• Beobachtetes Molekulargewicht: 59-65 kDa
• GenBank-Zugangsnummer: NM_080872
• Gene symbol: UNC5D
• Gene ID (NCBI): 137970
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

UNC5D, also named as KIAA1777 and UNC5H4, belongs to the unc-5 family. It is a receptor for netrin. It may be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5D.

Publikationen

Species	Application	Title
human		Sci Adv; The FLRT3-UNC5B checkpoint pathway inhibits T cell-based cancer immunotherapies; Authors - Kushal Prajapati