UPK1A Polyklonaler Antikörper

UPK1A Polyklonal Antikörper für IHC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25275-1-PBS

Synonyme

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  IP experiment of mouse bladder using 25275-1-AP (same clone as 25275-1-PBS)

  IP result of anti-UPK1A (IP:25275-1-AP, 4ug; Detection:25275-1-AP 1:300) with mouse bladder tissue lysate 3200ug. This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

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  IHC staining of human bladder using 25275-1-AP (same clone as 25275-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 25275-1-AP (UPK1A antibody) at dilution of 1:5000 (under 10x lens).. This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human bladder using 25275-1-AP (same clone as 25275-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 25275-1-AP (UPK1A antibody) at dilution of 1:5000 (under 40x lens).. This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse bladder using 25275-1-AP (same clone as 25275-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse bladder tissue slide using 25275-1-AP (UPK1A antibody) at dilution of 1:16000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse bladder using 25275-1-AP (same clone as 25275-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse bladder tissue slide using 25275-1-AP (UPK1A antibody) at dilution of 1:16000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat bladder using 25275-1-AP (same clone as 25275-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat bladder tissue slide using 25275-1-AP (UPK1A antibody) at dilution of 1:16000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat bladder using 25275-1-AP (same clone as 25275-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat bladder tissue slide using 25275-1-AP (UPK1A antibody) at dilution of 1:16000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

25275-1-PBS bindet in IHC, IP, Indirect ELISA UPK1A und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: UPK1A fusion protein Ag17356
• Vollständiger Name: uroplakin 1A
• Berechnetes Molekulargewicht: 258 aa, 29 kDa
• Beobachtetes Molekulargewicht: 29 kDa
• GenBank-Zugangsnummer: BC107098
• Gene symbol: UPK1A
• Gene ID (NCBI): 11045
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention (PMID: 8175808). Uroplakin-1a (UPK1A) belongs to the tetraspanin (TM4SF) family. UPK1A plays an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane.