UQCRC1 Rekombinanter Antikörper

• Featured Product
• KD/KO Validated

UQCRC1 Rekombinant Antikörper für WB, IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

CloneNo.

240507A6

Kat-Nr. : 83671-2-PBS

Synonyme

240507A6, Complex III subunit 1, Core protein I, Cytochrome b-c1 complex subunit 1, mitochondrial, D3S3191

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  WB analysis using 83671-2-RR (same clone as 83671-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83671-2-RR (UQCRC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83671-2-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 83671-2-RR (same clone as 83671-2-PBS)

  WB result of UQCRC1 antibody (83671-2-RR; 1:20000; incubated at room temperature for 1.5 hours) with sh-Control and sh-UQCRC1 transfected HeLa cells. This data was developed using the same antibody clone with 83671-2-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 83671-2-RR (same clone as 83671-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 83671-2-RR (UQCRC1 antibody) at dilution of 1:2000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer(pH9). This data was developed using the same antibody clone with 83671-2-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 83671-2-RR

  Biolayer interferometry (BLl) kinetic assays of 83671-2-RR against Human UQCRC1 were performed. The affinity constant is 0.294 nM.

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Geprüfte Anwendungen

Produktinformation

83671-2-PBS bindet in WB, IHC, ELISA UQCRC1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: UQCRC1 fusion protein Ag16322
• Vollständiger Name: ubiquinol-cytochrome c reductase core protein I
• Berechnetes Molekulargewicht: 480 aa, 53 kDa
• Beobachtetes Molekulargewicht: 45 kDa
• GenBank-Zugangsnummer: BC009586
• Gene symbol: UQCRC1
• Gene ID (NCBI): 7384
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

UQCRC1(Cytochrome b-c1 complex subunit 1, mitochondrial), also named as QCR1 and UQCR1, is a ubunit of the cytochrome bc1 complex (complex III) of the mitochondrial respiratory chain, may mediate the formation of the complex between cytochromes c and c1. The gene encodes a 53 kDa protein with a 34 amino acids transit peptide. It is associated with apoptosis or inhibition of cancer cell growth.