URAT1 Polyklonaler Antikörper

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• KD/KO Validated

URAT1 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14937-1-PBS

Synonyme

SLC22A12, RST, Renal-specific transporter, Renal specific transporter, Organic anion transporter 4-like protein

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  WB analysis using 14937-1-AP (same clone as 14937-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14937-1-AP (URAT1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.

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  WB analysis of pig kidney using 14937-1-AP (same clone as 14937-1-PBS)

  pig kidney tissue were subjected to SDS PAGE followed by western blot with 14937-1-AP (URAT1 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 14937-1-AP (same clone as 14937-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 14937-1-AP (URAT1 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 14937-1-AP (same clone as 14937-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 14937-1-AP (URAT1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

14937-1-PBS bindet in WB, IHC, Indirect ELISA URAT1 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

• Getestete Reaktivität: Hausschwein, human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: URAT1 fusion protein Ag6770
• Vollständiger Name: solute carrier family 22 (organic anion/urate transporter), member 12
• Berechnetes Molekulargewicht: 60 kDa
• Beobachtetes Molekulargewicht: 65-70 kDa, 40 kDa
• GenBank-Zugangsnummer: BC053348
• Gene symbol: URAT1
• Gene ID (NCBI): 116085
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Human urate anion exchanger (URAT1), also known as SLC22A12, is a urate transporter located in the proximal tubules of human kidney and responsible for urate reabsorption. Defects in gene encoding URAT1 cause hypouricemia renal type 1 (RHUC1). This antibody recognizes the native and glycosylated URAT1 between 65 and 70 kDa as well as the truncated 40kDa protein.