USP22 Monoklonaler Antikörper

USP22 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3D11H9

Kat-Nr. : 60905-1-PBS

Synonyme

Deubiquitinating enzyme 22, EC:3.4.19.12, KIAA1063, Ubiquitin carboxyl-terminal hydrolase 22, Ubiquitin thioesterase 22

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  WB analysis using 60905-1-Ig (same clone as 60905-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60905-1-Ig (USP22 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60905-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

60905-1-PBS bindet in WB, Indirect ELISA USP22 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: USP22 fusion protein Ag34933
• Vollständiger Name: ubiquitin specific peptidase 22
• Berechnetes Molekulargewicht: 60 kDa
• Beobachtetes Molekulargewicht: 58 kDa
• GenBank-Zugangsnummer: NM_015276
• Gene symbol: USP22
• Gene ID (NCBI): 23326
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

USP22, also named as KIAA1063 and USP3L, belongs to the peptidase C19 family and UBP8 subfamily. It is histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. USP22 catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. It is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. USP22 is required for nuclear receptor-mediated transactivation and cell cycle progression. USP22 has 2 isoforms with molecular mass of 58kDa and 60 kDa. The antibody is specific to USP22.