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USP48 Rekombinanter Antikörper

USP48 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251394C2

Kat-Nr. : 86523-1-PBS

Synonyme

Deubiquitinating enzyme 48, EC:3.4.19.12, RAP1GA1, Ubiquitin carboxyl-terminal hydrolase 48, Ubiquitin thiolesterase 48

Filter:
  • Western Blot (WB) analysis of various lysates using USP48 Recombinant antibody (86523-1-RR)

    WB analysis using 86523-1-RR (same clone as 86523-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86523-1-RR (USP48 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86523-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86523-1-PBS bindet in WB, Indirect ELISA USP48 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen USP48 fusion protein Ag2749
Vollständiger Name ubiquitin specific peptidase 48
Berechnetes Molekulargewicht 1035 aa, 119 kDa
Beobachtetes Molekulargewicht120 kDa
GenBank-ZugangsnummerBC013567
Gene symbol USP48
Gene ID (NCBI) 84196
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

USP48 (Ubiquitin Specific Peptidase 48) is a deubiquitinating enzyme and a member of the Ubiquitin Specific Protease (USP) family. This protein specifically recognizes and cleaves ubiquitin chains on substrate proteins, reversing the ubiquitination process, thereby regulating the stability, activity, and subcellular localization of target proteins. USP48 plays a key role in various cellular processes, including DNA damage repair, cell cycle regulation, and gene transcription. Studies have shown that USP48 is closely related to pathological processes such as cancer and neurodegenerative diseases, for example, by stabilizing transcription factors or signaling pathway proteins to influence tumor development.