UTP23 Polyklonaler Antikörper

UTP23 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen(1)

Kat-Nr. : 15950-1-AP

Synonyme

rRNA-processing protein UTP23 homolog, C8orf53

---

• 

  WB analysis of mouse liver using 15950-1-AP

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 15950-1-AP (UTP23 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse liver using 15950-1-AP

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 15950-1-AP (UTP23 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Mauslebergewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below
• IHC: See 1 publications below

Produktinformation

15950-1-AP bindet in WB, IHC, ELISA UTP23 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: UTP23 fusion protein Ag8609
• Vollständiger Name: UTP23, small subunit (SSU) processome component, homolog (yeast)
• Berechnetes Molekulargewicht: 249 aa, 28 kDa
• Beobachtetes Molekulargewicht: 28 kDa, 17 kDa
• GenBank-Zugangsnummer: BC005955
• Gene symbol: UTP23
• Gene ID (NCBI): 84294
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

UTP23 is a component of ribosomal small-subunit processome, which is involved in ribosome synthesis and RNA maturation. UTP23 contains a long and likely unstructured tail at the C terminus of the PIN domain (PMID: 24152547). UTP23 is a target of genetic variation associated with colorectal cancer in chromosome 8q23.3, and it may coordinate with EIF3H in this region in the development of colorectal cancer. Low expression of UTP23 predicts poorer prognosis of ovarian cancer patients (PMID: 31540773, 37880005). It has 2 predicted molecular weight of 28 kDa and 17 kDa.

Publikationen

Species	Application	Title
human	WB,IHC	Clin Breast Cancer; UTP23 Functions in Breast Cancer Progression and Predicts Poor Prognosis of Luminal a Breast Cancer; Authors - Sida Zhang