UTY Rekombinanter Antikörper

UTY Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241626F7

Kat-Nr. : 84332-5-PBS

Synonyme

UTY1, KDM6C, KDM6AL, Histone demethylase UTY, 241626F7

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  WB analysis using 84332-5-RR (same clone as 84332-5-PBS)

  THP-1 cells were subjected to SDS PAGE followed by western blot with 84332-5-RR (UTY antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84332-5-PBS in a different storage buffer formulation.

• 

  IF Staining of MDA-MB-231 using 84332-5-RR (same clone as 84332-5-PBS)

  Immunofluorescent analysis of (4% PFA) fixed MDA-MB-231 cells using UTY antibody (84332-5-RR, Clone: 241626F7 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84332-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84332-5-RR

  Biolayer interferometry (BLl) kinetic assays of 84332-5-RR against Human UTY were performed. The affinity constant is 0.23 nM.

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Geprüfte Anwendungen

Produktinformation

84332-5-PBS bindet in WB, IF/ICC, Indirect ELISA UTY und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: UTY fusion protein Ag35806
• Vollständiger Name: ubiquitously transcribed tetratricopeptide repeat gene, Y-linked
• Berechnetes Molekulargewicht: 150kDa，1347aa
• Beobachtetes Molekulargewicht: 130-160kDa
• GenBank-Zugangsnummer: NM_007125.4
• Gene symbol: UTY
• Gene ID (NCBI): 7404
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

UTY (Ubiquitously Transcribed Tetratricopeptide Repeat Containing, Y-Linked) is a protein-coding gene located on the Y chromosome. It is the Y-linked homolog of the X-linked gene KDM6A, which encodes a histone demethylase. UTY is involved in the regulation of gene expression and chromatin structure, similar to its X-linked counterpart KDM6A (PMID: 31097364). UTY is expressed in various tissues and is predicted to be involved in transcription, translation, and nucleic acid binding, which are central to the regulation of gene expression during development, immune function, cell proliferation, and differentiation.