UXT Polyklonaler Antikörper
UXT Polyklonal Antikörper für WB, IP, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IP, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 11047-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
11047-1-PBS bindet in WB, IP, Indirect ELISA UXT und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | UXT fusion protein Ag1513 |
| Vollständiger Name | ubiquitously-expressed transcript |
| Berechnetes Molekulargewicht | 20 kDa |
| Beobachtetes Molekulargewicht | 18 kDa, 45 kDa |
| GenBank-Zugangsnummer | BC008890 |
| Gene symbol | UXT |
| Gene ID (NCBI) | 8409 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Ubiquitously expressed transcript (UXT) is a gene transcription regulator. It can regulate androgen receptor(AR) transcription by concerting with the coreperssor UR1. It is proposed a potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling, for UXT increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC. UXT is possible a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function. It can suppresses cell transformation and mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM





