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VAT1 Rekombinanter Antikörper

VAT1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251841D6

Kat-Nr. : 86847-1-PBS

Synonyme

EC:1.-.-.-, Synaptic vesicle membrane protein VAT-1 homolog, VATI

Filter:
  • Western Blot (WB) analysis of various lysates using VAT1 Recombinant monoclonal antibody (86847-1-RR)

    WB analysis using 86847-1-RR (same clone as 86847-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86847-1-RR (VAT1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86847-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using VAT1 Recombinant monoclonal antibody (86847-1-RR)

    WB analysis using 86847-1-RR (same clone as 86847-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86847-1-RR (VAT1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86847-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86847-1-PBS bindet in WB, Indirect ELISA VAT1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen VAT1 fusion protein Ag16652
Vollständiger Name vesicle amine transport protein 1 homolog (T. californica)
Berechnetes Molekulargewicht 42 kDa
Beobachtetes Molekulargewicht 45 kDa
GenBank-ZugangsnummerBC015041
Gene symbol VAT1
Gene ID (NCBI) 10493
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Vesicle amine transport protein 1 (VAT1) is expressed in neurons and neuroendocrine cells, where it participates in vesicular monoamine uptake and in the docking/fusion steps of neurotransmitter release. Beyond the nervous system, VAT1 binds anionic phospholipids (phosphatidic acid and phosphatidylserine) and catalyses their inter-membrane transfer, thereby integrating lipid metabolism with vesicle trafficking. Recent tumour-biology studies have revealed that VAT1 is frequently up-regulated in aggressive gliomas and gastric cancers; its abundance correlates with enhanced cell migration, radioresistance and an immunosuppressive micro-environment. (PMID: 39832459,PMID: 31524269)