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VCP Monoklonaler Antikörper

VCP Monoklonal Antikörper für WB, IHC, IF/ICC, FC (Intra), ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, IF/ICC, FC (Intra), ELISA

Konjugation

Unkonjugiert

CloneNo.

2A4B10

Kat-Nr. : 60316-1-PBS

Synonyme

15S Mg(2+) ATPase p97 subunit, 15S Mg(2+)-ATPase p97 subunit, 2A4B10, EC:3.6.4.6, HEL-220



Geprüfte Anwendungen

Produktinformation

60316-1-PBS bindet in WB, IHC, IF/ICC, FC (Intra), ELISA VCP und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen VCP fusion protein Ag1002
Vollständiger Name valosin-containing protein
Berechnetes Molekulargewicht 89 kDa
Beobachtetes Molekulargewicht 89 kDa
GenBank-ZugangsnummerBC007562
Gene symbol VCP
Gene ID (NCBI) 7415
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

VCP(Valosin-containing protein), also known as TER ATPase and 15S Mg2+-ATPase p97 subunit, belongs to the AAA ATPase family. VCP was first identified as a result of attempts to clone a putative peptide hormone called valosin. It was found that the cloned cDNA encoded a ubiquitously expressed 90 kDa cytosolic protein, termed VCP, which showed none of the characteristics of a peptide hormone precursor(PMID:1382975). Defects in VCP are the cause of inclusion body myopathy with early-onset Paget disease and frontotemporal dementia (IBMPFD) and amyotrophic lateral sclerosis type 14 with or without frontotemporal dementia (ALS14). VCP has a calculated molecular weight of 89 kDa and an apparent molecular weight of 90-100 kDa (PMID: 15732117, 1382975).