VE-cadherin/CD144 Monoklonaler Antikörper

VE-cadherin/CD144 Monoklonal Antikörper für WB, IHC, IF-P, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, IHC, IF-P, ELISA

Konjugation

Unkonjugiert

CloneNo.

4F9B10

Kat-Nr. : 66804-1-PBS

Synonyme

VE-cadherin, 4F9B10, 7B4, 7B4 antigen, Cadherin 5



Geprüfte Anwendungen

Produktinformation

66804-1-PBS bindet in WB, IHC, IF-P, ELISA VE-cadherin/CD144 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen VE-cadherin/CD144 fusion protein Ag27501
Vollständiger Name cadherin 5, type 2 (vascular endothelium)
Berechnetes Molekulargewicht 88 kDa
Beobachtetes Molekulargewicht125 kDa, 100 kDa
GenBank-ZugangsnummerNM_001795
Gene symbol VE-cadherin
Gene ID (NCBI) 1003
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. Vascular endothelial cadherin (VE-cadherin), also known as Cadherin-5 (CDH5) or CD144, is a member of the type II classical cadherin family of cell adhesion proteins (PMID: 21269602). VE-cadherin is expressed specifically in endothelial cells and mediates homophilic adhesion in the vascular endothelium (PMID: 1522121; 8555485; 21269602). VE-cadherin plays a role in the organization of lateral endothelial junctions and in the control of permeability properties of vascular endothelium (PMID: 1522121). VE-cadherin has also been shown to be required for angiogenesis (PMID: 16473763; 18162609).