VEGFA Rekombinanter Antikörper
VEGFA Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus
Anwendung
WB, IF/ICC, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
7H10
Kat-Nr. : 81323-2-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
81323-2-PBS bindet in WB, IF/ICC, Indirect ELISA VEGFA und zeigt Reaktivität mit human, Maus
Getestete Reaktivität | human, Maus |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | VEGFA fusion protein Ag13500 |
Vollständiger Name | vascular endothelial growth factor A |
Berechnetes Molekulargewicht | 412 aa, 46 kDa |
Beobachtetes Molekulargewicht | 40 kDa |
GenBank-Zugangsnummer | BC065522 |
Gene symbol | VEGFA |
Gene ID (NCBI) | 7422 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are associated with microvascular complications of diabetes type 1 (MVCD1). VEGFA has 17 isoforms with MW from 16 to 45 kDa. Some isoforms have homodimer forms (e.g.; VEGFA189 38 kDa or VEFGA110 34 kDa). VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids (PMID:15602010 ).