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VLDLR Polyklonaler Antikörper

VLDLR Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 19493-1-PBS

Synonyme

VLDL-R, VLDL receptor, Very low-density lipoprotein receptor

Filter:
  • Western Blot (WB) analysis of various lysates using VLDLR Polyclonal antibody (19493-1-AP)

    WB analysis using 19493-1-AP (same clone as 19493-1-PBS)

    MCF-7 cells were subjected to SDS PAGE followed by western blot with 19493-1-AP (VLDLR antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19493-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using VLDLR Polyclonal antibody (19493-1-AP)

    IF Staining of HeLa using 19493-1-AP (same clone as 19493-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using VLDLR antibody (19493-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 19493-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

19493-1-PBS bindet in WB, IF/ICC, Indirect ELISA VLDLR und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name very low density lipoprotein receptor
Berechnetes Molekulargewicht 96 kDa
Beobachtetes Molekulargewicht 96 kDa
GenBank-ZugangsnummerNM_003383
Gene symbol VLDLR
Gene ID (NCBI) 7436
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

VLDLR binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. VLDLR binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (cytoplasmic domain of low-density lipoprotein receptor). For glycosylated, the MW of VLDLR migrates to ~160kd.