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WBSCR17 Rekombinanter Antikörper

WBSCR17 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250868B10

Kat-Nr. : 86351-1-PBS

Synonyme

EC:2.4.1.41, GalNAc T like protein 3, GalNAc-T-like protein 3, GALNT17, Polypeptide GalNAc transferase-like protein 3

Filter:
  • Western Blot (WB) analysis of various lysates using WBSCR17 Recombinant antibody (86351-1-RR)

    WB analysis using 86351-1-RR (same clone as 86351-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86351-1-RR (WBSCR17 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86351-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86351-1-RR

    Affinity and Kinetic Characterization of 86351-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86351-1-RR against Human WBSCR17 were performed. The affinity constant is 1.25 nM.

Geprüfte Anwendungen

Produktinformation

86351-1-PBS bindet in WB, Indirect ELISA WBSCR17 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen WBSCR17 fusion protein Ag15792
Vollständiger Name Williams-Beuren syndrome chromosome region 17
Berechnetes Molekulargewicht 598 aa, 68 kDa
Beobachtetes Molekulargewicht70~90 kDa
GenBank-ZugangsnummerBC069624
Gene symbol WBSCR17
Gene ID (NCBI) 64409
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

WBSCR17, also known as GALNT17, which encodes a brain-expressed N-acetylgalactosaminyl transferase (GalNAcT), is located at the distal edge of a region that is commonly deleted or duplicated in Williams Beuren Syndrome (WBS), a developmental disorder with motor and coordination problems, impaired visuospatial memory, and abnormal social interaction (PMID: 31554716). WBSCR17 loss-of-function has significant effects on cerebellar development, and is associated with phenotypes including developmental delay, deficits in motor coordination, reduced exploratory activity, and impaired social behavior (PMID: 22787146). With the calculated molecular mass of recombinant WBSCR17 being 68 kDa, the 70-90-kDa glycoproteins could also be detected due to post-translational modifications (PMID: 22787146).