WDFY2 Polyklonaler Antikörper

WDFY2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17197-1-PBS

Synonyme

ZFYVE22, WDF2, WD40- and FYVE domain-containing protein 2, WD repeat and FYVE domain-containing protein 2, Propeller-FYVE protein

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  WB analysis using 17197-1-AP (same clone as 17197-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17197-1-AP (WDFY2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17197-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

17197-1-PBS bindet in WB, Indirect ELISA WDFY2 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: WDFY2 fusion protein Ag10415
• Vollständiger Name: WD repeat and FYVE domain containing 2
• Berechnetes Molekulargewicht: 400 aa, 45 kDa
• Beobachtetes Molekulargewicht: 45 kDa
• GenBank-Zugangsnummer: BC014004
• Gene symbol: WDFY2
• Gene ID (NCBI): 115825
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

WDFY2, also named Prof, is a protein that contains WD repeats and an FYVE domain. WDFY2 regulates the membrane-bound matrix metalloproteinase MT1-MMP (MMP14) efflux by controlling endosome sorting. WDFY2 may act as a tumor suppressor by limiting VAMP3-dependent recycling to inhibit matrix metalloproteinase secretion and cell invasion. (PMID: 31253801)