WDR62 Polyklonaler Antikörper

WDR62 Polyklonal Antikörper für IHC, IF/ICC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, IF/ICC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23404-1-PBS

Synonyme

C19orf14, WD repeat domain 62, WD repeat-containing protein 62

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  IP experiment of HEK-293T using 23404-1-AP (same clone as 23404-1-PBS)

  IP result of anti-WDR62 (IP:23404-1-AP, 4ug; Detection:23404-1-AP 1:500) with HEK-293T cells lysate 1320 ug. This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 23404-1-AP (same clone as 23404-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 23404-1-AP (WDR62 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 23404-1-AP (same clone as 23404-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 23404-1-AP (WDR62 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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  IF Staining of hTERT-RPE1 using 23404-1-AP (same clone as 23404-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed hTERT-RPE1 cells using WDR62 antibody (23404-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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  IF Staining of A549 using 23404-1-AP (same clone as 23404-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using WDR62 antibody (23404-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 23404-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

23404-1-PBS bindet in IHC, IF/ICC, IP, Indirect ELISA WDR62 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: WDR62 fusion protein Ag19865
• Vollständiger Name: WD repeat domain 62
• Berechnetes Molekulargewicht: 1518 aa, 166 kDa
• Beobachtetes Molekulargewicht: 180 kDa
• GenBank-Zugangsnummer: BC017261
• Gene symbol: WDR62
• Gene ID (NCBI): 284403
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-affinitätsgereinigt
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The WD40-repeat protein 62 (WDR62) is a scaffold protein that recruits different components of the JNK signaling pathway to regulate several human diseases including neurological disorders, infertility, and tumorigenesis (PMID: 33937237). Moreover, WDR62 participates in diverse biological processes, especially mitotic spindle organization via regulating centriole biogenesis and the function of centriole-associated protein (PMID: 35093571).