WDR77 Polyklonaler Antikörper
WDR77 Polyklonal Antikörper für WB, IHC, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, IHC, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 10115-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
10115-1-PBS bindet in WB, IHC, Indirect ELISA WDR77 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | WDR77 fusion protein Ag0147 |
| Vollständiger Name | WD repeat domain 77 |
| Berechnetes Molekulargewicht | 50 kDa |
| Beobachtetes Molekulargewicht | 40 kDa |
| GenBank-Zugangsnummer | BC001679 |
| Gene symbol | WDR77 |
| Gene ID (NCBI) | 79084 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
WDR77, other named p44, MEP-50, is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. Normally, WDR77 locates in the nucleus, such as in prostate epithelial cells. However, it localized to the cytoplasm in prostatic intraepithelial neoplasia and prostate cancer cells. Nuclear WDR77 mediates the growth inhibition and differentiation. WDR may involve in the biogenesis of small nuclear ribonucleoprotein particles.



