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WNK3 Polyklonaler Antikörper

WNK3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32231-1-PBS

Synonyme

Serine/threonine-protein kinase WNK3, Protein kinase with no lysine 3, Protein kinase lysine-deficient 3, PRKWNK3, KIAA1566

Filter:
  • Western Blot (WB) analysis of various lysates using WNK3 Polyclonal antibody (32231-1-AP)

    WB analysis using 32231-1-AP (same clone as 32231-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32231-1-AP (WNK3 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32231-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32231-1-PBS bindet in WB, Indirect ELISA WNK3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen WNK3 fusion protein Ag37713
Vollständiger Name WNK lysine deficient protein kinase 3
Berechnetes Molekulargewicht1800aa, 198 kDa
Beobachtetes Molekulargewicht230 kDa
GenBank-ZugangsnummerNM_001002838
Gene symbol WNK3
Gene ID (NCBI) 65267
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

WNK3, is a member of the WNK (With No Lysine [K]) kinase family. It is a serine/threonine kinase that plays important roles in various physiological processes. WNK3 is expressed in brain, lung, kidney, liver and pancreas, and in fetal tissues including placenta, fetal brain, lung and kidney. Very low levels of expression were also detected in fetal heart, thymus, liver and spleen. Isoform 1 is brain-specific. Isoform 3 is kidney-specific. Endogenous WNK3 protein is an active protein kinase when immunoprecipitated from cells and its overexpression increases the survival of HeLa cells by delaying the onset of apoptosis (PMID:16501604).