WNT4 Polyklonaler Antikörper

WNT4 Polyklonal Antikörper für IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14371-1-PBS

Synonyme

WNT 4, UNQ426/PRO864, SERKAL, Protein Wnt-4, Protein Wnt 4

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  IHC staining of human kidney using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 14371-1-AP (WNT4 antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 14371-1-AP (WNT4 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 14371-1-AP (WNT4 antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IHC staining of human hepatocirrhosis using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis tissue slide using 14371-1-AP (WNT4 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IHC staining of human hepatocirrhosis using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis tissue slide using 14371-1-AP (WNT4 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 14371-1-AP (WNT4 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 14371-1-AP (same clone as 14371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 14371-1-AP (WNT4 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 14371-1-AP (same clone as 14371-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using WNT4 antibody (14371-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002), CL594-Phalloidin (red). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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  IF Staining of MCF-7 using 14371-1-AP (same clone as 14371-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using WNT4 antibody (14371-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 14371-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

14371-1-PBS bindet in IHC, IF/ICC, Indirect ELISA WNT4 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: WNT4 fusion protein Ag5741
• Vollständiger Name: wingless-type MMTV integration site family, member 4
• Berechnetes Molekulargewicht: 39 kDa
• Beobachtetes Molekulargewicht: 39-45 kDa
• GenBank-Zugangsnummer: BC057781
• Gene symbol: WNT4
• Gene ID (NCBI): 54361
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

WNT4 belongs to the Wnt family. WNT4 is critical for embryonic organogenesis, but later plays a unique role among Wnt proteins in the development and maintenance of müllerian and reproductive tissues (PMID: 33963381). The mesenchymal stem cells can improve cardiac function after cardiac injury by regulating endothelial cells via the Wnt4/β-catenin signaling pathway (PMID: 20551912). WNT4 may be modified by glycosylation, leading to an increase in molecular weight.