WNT6 Polyklonaler Antikörper

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• KD/KO Validated

WNT6 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24201-1-PBS

Synonyme

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  WB analysis of SGC-7901 using 24201-1-AP (same clone as 24201-1-PBS)

  SGC-7901 cells were subjected to SDS PAGE followed by western blot with 24201-1-AP (WNT6 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24201-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 24201-1-AP (same clone as 24201-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24201-1-AP (WNT6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24201-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 24201-1-AP (same clone as 24201-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24201-1-AP (WNT6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24201-1-PBS in a different storage buffer formulation.

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  IHC staining of human small intestine using 24201-1-AP (same clone as 24201-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 24201-1-AP (WNT6 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 24201-1-PBS in a different storage buffer formulation.

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  IHC staining of human small intestine using 24201-1-AP (same clone as 24201-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 24201-1-AP (WNT6 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 24201-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

24201-1-PBS bindet in WB, IHC, Indirect ELISA WNT6 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: WNT6 fusion protein Ag20889
• Vollständiger Name: wingless-type MMTV integration site family, member 6
• Berechnetes Molekulargewicht: 39 kDa
• Beobachtetes Molekulargewicht: 42 kDa
• GenBank-Zugangsnummer: BC004329
• Gene symbol: WNT6
• Gene ID (NCBI): 7475
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

WNT6 belongs to the Wnt family. It is ligand for members of the frizzled family of seven transmembrane receptors. WNT6 is likely to signal over only few cell diameters. WNT6 may be together with CAV1 to promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway. And WNT6 is mainly expressed in brain, endometrium epithelium, gastric cancer cell lines and gastric cancer tissues (PMID: 22370641).