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WRN Polyklonaler Antikörper

WRN Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25269-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of MCF-7 cells using WRN Polyclonal antibody (25269-1-AP)

    WB analysis of MCF-7 using 25269-1-AP (same clone as 25269-1-PBS)

    MCF-7 cells were subjected to SDS PAGE followed by western blot with 25269-1-AP (WRN Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25269-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HEK-293 cells using WRN Polyclonal antibody (25269-1-AP)

    WB analysis of HEK-293 using 25269-1-AP (same clone as 25269-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 25269-1-AP (WRN Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25269-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25269-1-PBS bindet in WB, Indirect ELISA WRN und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name Werner syndrome, RecQ helicase-like
Berechnetes Molekulargewicht 162 kDa
Beobachtetes Molekulargewicht 162 kDa
GenBank-ZugangsnummerNM_000553
Gene symbol WRN
Gene ID (NCBI) 7486
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Werner syndrome ATP dependent helicase (WRN) ,also named as RECQ3 or RecQ protein like 2, is a 1432 amino acid protein, which contains one HRDC domain, one helicase C-terminal domain, one helicase ATP-binding domain and 3'-5' exonuclease domain. WRN localizes in the nucleoplasm and belongs to the helicase family. WRN plays a central role in the repair of methylation-induced DNA damage and has an helicase activity necessary to prevent dramatic telomere loss during DNA replication. WRN gene mutation has an association with Werner syndrome and colorectal cancer.