WWOX Monoklonaler Antikörper

WWOX Monoklonal Antikörper für WB, IHC, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, IHC, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1B8F4

Kat-Nr. : 67725-1-PBS

Synonyme

FRA16D, FOR1, FOR, EC:1.1.1.-, D16S432E

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  WB analysis using 67725-1-Ig (same clone as 67725-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67725-1-Ig (WWOX antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67725-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 67725-1-Ig (same clone as 67725-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 67725-1-Ig (WWOX antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67725-1-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP51258-1

  Cytometric bead array standard curve of MP51258-1, WWOX Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67725-2-PBS. Detection antibody: 67725-1-PBS. Standard:Ag7969. Range: 0.195-100 ng/mL.

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Geprüfte Anwendungen

Produktinformation

67725-1-PBS bindet in WB, IHC, Cytometric bead array, Indirect ELISA WWOX und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

• Getestete Reaktivität: Hausschwein, human, Maus, Ratte
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: WWOX fusion protein Ag7969
• Vollständiger Name: WW domain containing oxidoreductase
• Berechnetes Molekulargewicht: 47 kDa
• Beobachtetes Molekulargewicht: 40 kDa
• GenBank-Zugangsnummer: BC003184
• Gene symbol: WWOX
• Gene ID (NCBI): 51741
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

WWOX(WW domain-containing oxidoreductase) is also named as FOR, WOX1 and belongs to the short-chain dehydrogenases/reductases (SDR) family. The gene encodes a 46 kDa protein that contains two WW domains and a short-chain dehydrogenase/reductase domain and the protein is lost or reduced in the majority of many cancer types including breast, prostate, esophageal, lung, stomach, and pancreatic carcinomas and in a large fraction of other cancer types(PMID:17360458). WWOX behaves as a potential tumor-suppressor gene(PMID:15064722). It has 7 isoforms produced by alternative splicing.